EPC |
Total protein, albumin, and
all globulin fractions within reference intervals.
|
Albumin |
EPX |
Hypoalbuminemia
|
EPX1 |
Hypoalbuminemia consistent
with albumin wasting disorder.
|
EPH
(see also EPY) |
Hypoalbuminemia. Decreased
alpha-2 globulins. Hypergamma-globulinemia
with beta-gamma bridging. Pattern consistent with chronic inflammatory
hepatic disorder (?cirrhosis). |
ADA |
If albumin
differs between SPEP and ordered (routine
chem.), this comment can be used at the discretion of the reviewer. It
should FOLLOW all other interpretations.
Visual interpretation of the
electrophoretic
pattern suggests
decreased albumin, confirmed at __g/dL by an accurate (immunochemical
; chemical) method. |
Alpha-1
globulins |
EPD |
Increased alpha-1 globulins
(alpha-1-antitrypsin, acute phase reactant)
|
EPD1 |
Decreased alpha-1 globulins
(alpha-1-antitrypsin, acute phase reactant). We recommend alpha-1
antitrypsin quantitation and phenotyping, if clinically indicated. |
Alpha-2
globulins |
EPJ |
Increased alpha-2 globulins (haptoglobin
and alpha-2 macroglobulin, acute phase reactants)
|
EPJ1 |
Decreased alpha-2 globulins (haptoglobin
and alpha-2 macroglobulin, acute phase reactants)
|
EPM |
Pattern is consistent with
non-selective protein loss and/or underproduction with a compensatory
increase in alpha-2 globulin production. |
Beta globulins |
EPE |
Increased beta-1 globulins (transferrin
and beta lipoproteins, acute phase
reactants). |
EPE 1 |
Decreased beta-1 globulins
(transferrin and beta lipoproteins, acute
phase reactants).
|
Gamma globulins |
EPN
|
Hypogammaglobulinemia |
EPA |
Hypergammaglobulinemia of
polyclonal origin. Pattern is consistent with inflammatory process.
|
EPY |
(confluence
between the beta and gamma zones (beta-gamma bridging)
or
increased
beta globulins, secondary to bridging with gamma zone) .
Pattern is consistent with
chronic inflammatory disorder (?cirrhosis.) |
EPO |
Hypergammaglobulinemia with
multiple small discrete bands detected within a broad zone of increased
polyclonal gamma globulins. This pattern is suggestive of an
oligoclonal expansion of a restricted number of B-cell clones
associated with active hepatic inflammation, autoimmune, immunodeficient,
or immunosuppressive conditions involving
altered immunoregulatory mechanisms. We recommend serum immunofixation
electrophoresis for clarification, if clinically indicated. |
EPL |
Polyclonal
immunoglobulins appear (mildly,
moderately, severely) decreased; estimated level is _________g/dL.
(Interpreter: fill in the blank by
subtracting total gamma, g/dL – abnormal protein, g/dL)
|
EPK |
A discrete band representing
an M-protein, previously identified by immunofixation electrophoresis
(alternately write clinically classified) as ___is detected at a
level of __g/dL in the __zone. Previous level was ___g/dL on
_ / /__.
|
EPK 1 |
The prominent (or other
modifier ) monoclonal ______ protein is
detected at a level of ______g/dL (use alternate appropriate units for
urine) in the _____zone. Previous level was _____g/dL (or alternate
units) on _ / /__.
|
EPZ
|
No monoclonal bands seen.
|
EPZ1 |
No monoclonal or oligoclonal
bands seen |